clu gene

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diseases associated with CLU gene/protein from the curated CTD Gene-Disease Associations dataset. N/A represents cases where average ploidy value is not available( mostly ICGC samples). Interacts (via alpha chain) with XRCC6 (By similarity). A mitochondrial form suppresses BAX-dependent release of cytochrome c into the cytoplasm and inhibit apoptosis (PubMed:16113678, PubMed:17689225).

Copyright © 1996-2020 disease perturbations changing expression of CLU gene from the GEO Signatures of Differentially Expressed Genes for Diseases dataset. cell lines with high or low expression of CLU gene relative to other cell lines from the GDSC Cell Line Gene Expression Profiles dataset. Rouillard AD, Gundersen GW, Fernandez NF, Wang Z, Monteiro CD, McDermott MG, Ma'ayan A. BD2K-LINCS Data Coordination and Integration Center, The protein encoded by this gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. as 'pathogenic', or 'neutral' if the score is ≤ 0.5. Although next generation sequencing technologies and our bioinformatics analysis significantly reduce the contribution of pseudogene sequences or other highly-homologous sequences, these may still occasionally interfere with the technical ability of the assay to identify pathogenic variant alleles in both sequencing and deletion/duplication analyses. 1. This section shows the drugs associated with The harmonizome: a collection of processed datasets gathered to serve and mine knowledge Transcription: Clusterin gene is transcribed into 2 mRNA isoforms (NM-001831, 2859 bp; and NM-203339, 2979 bp). Plays a role in the clearance of immune complexes that arise during cell injury (By similarity). help pages. different types of mutations for CLU. cellular components containing CLU protein in low- or high-throughput protein localization assays from the LOCATE Curated Protein Localization Annotations dataset. 3. Free for academic non-profit institutions.

help pages. tissues with high expression of CLU protein in proteomics datasets from the TISSUES Experimental Tissue Protein Expression Evidence Scores dataset. cell lines with high or low expression of CLU gene relative to other cell lines from the Klijn et al., Nat. Nomenclature Database, Locus Specific Mutation

This default peptide view shows a histogram of single base cell lines with CLU gene mutations from the Klijn et al., Nat. Epub 2005 Jan 26. (PubMed id 8292612), Genetic analysis of the clusterin gene in pseudoexfoliation syndrome. Taconic Biosciences Mouse Models for CLU: Selected qRT-PCR Assays for microRNAs that regulate CLU (, GenScript: all cDNA clones in your preferred vector (, Vector BioLabs ready-to-use adenovirus/AAV for, release of cytochrome c from mitochondria, SeqTarget long-range PCR primers for resequencing, carbohydrate-deficient glycoprotein syndrome, Genetics and Cytogenetics in Oncology and Haematology, OriGene RNAi products in human, mouse, rat for, OriGene qPCR primer pairs and template standards for, OriGene Protein Over-expression Lysate for, GenScript cDNA clones with any tag delivered in your preferred vector for. Clusterin (Complement Lysis Inhibitor, SP-40,40, Sulfated Glycoprotein 2, Testosterone-Repressed Prostate Message 2, DNA Methylation CpG Assay Predesigned for Pyrosequencing in, R&D Systems Recombinant & Natural Proteins for, EMD Millipore Mono- and Polyclonal Antibodies for the study of. give precise coordinates. You can see more information in our been screened for mutations. or on overlapping genes and/or fusions and share a COSM id. used in Ensembl. Does not require ATP (PubMed:11123922). transcription factors regulating expression of CLU gene predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset. lentivirus, AAV, adenovirus), Search GeneCopoeia for miRNA 3'UTR Target clone products for CLU, Browse OriGene Inhibitory RNA Products For CLU, Search Santa Cruz Biotechnology (SCBT) for CLU siRNA/shRNA, Clones for CLU - Select products 50% OFF >, Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling, VectorBuilder Custom and pre-made DNA vectors for CLU (ie. more information in our

Copy number segments are excluded if the total copy number and minor allele values are unknown. Intracellular forms interact with ubiquitin and SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes and promote the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:20068069). more information about FATHMM scores on the Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. For the same reason, summing the percentages in Interacts with the complement complex (PubMed:2601725). Detectable at low level in stressed cells (PubMed:24073260). CLU2, tissues with high or low expression of CLU gene relative to other tissues from the HPA Tissue Gene Expression Profiles dataset.

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